Can diltiazem cause fluid retention?

Can diltiazem cause fluid retention?

Rhinitis, headache, sore throat, constipation, edema (fluid retention), skin rashes (although these are usually transient), and a lack of energy are the most commonly reported side effects.

Does diltiazem make your feet swell?

Common side effects include swollen hands, ankles or feet, headaches and constipation. Diltiazem starts to work on the day you start taking it, but for high blood pressure and angina it may take a couple of weeks to work fully.

Is edema a side effect of diltiazem?

edema (swelling of the legs and feet with fluid), low blood pressure (hypotension), drowsiness, and.

Is diltiazem safe during pregnancy?

From the class IV antiarrhythmic drugs, calcium channel blocking agents, such as verapamil and diltiazem, are considered to be relatively safe (category C). Also, unclassified adenosine and digoxin are considered to be relatively safe.

Does diltiazem cause ankle edema?

Ankle oedema appears to occur more frequently in CCBs from the DHP group, although some agents such as lacidipine and lercanidipine may cause it less frequently than nifedipine and amlodipine. Diltiazem, a non-DHP agent, seems to be associated with the lowest incidence of ankle oedema.

Can calcium channel blockers cause leg swelling?

Objective: Peripheral edema is considered to be a common and annoying adverse effect of calcium channel blockers (CCBs). It has been thought to occur secondary to arteriolar dilatation causing intracapillary hypertension and fluid extravasation.

Can diltiazem cause leg cramps?

16 cramps per phase; P = 0.040) in the frequency of leg cramps between those on diltiazem hydrochloride and those on placebo. There was no signi®cant difference (95% CI, ±0.30 to 0.11; P = 0.347) in the intensity of leg cramps between those on diltiazem hydrochloride and those on placebo.

Are calcium channel blockers safe in pregnancy?

Calcium channel blockers can be safely used during pregnancy and breastfeeding.

What blood pressure medicine is safe during pregnancy?

Methyldopa has been used for decades to treat high blood pressure in pregnancy and it appears to be safe. Labetalol has been extensively studied and has become increasing prescribed in pregnancy. Labetalol is now commonly used as a first-line treatment choice. Nifedipine is also sometimes used in certain situations.

What causes swelling in legs during pregnancy?

As your uterus grows it can put extra pressure on the blood vessels that carry blood from the lower part of your body back to your heart. This results in fluid retention, causing your swollen legs, ankles, and feet during your pregnancy. The medical term for swelling caused by fluid retention is edema.

Why do calcium channel blockers cause edema?

CCB-induced oedema is caused primarily by the increased capillary hydrostatic pressure that results from greater dilation of pre-capillary than post-capillary vessels.